Summary: Treatment options for IgA nephropathy (IgAN) must take into consideration the pathophysiology, namely the role joico lumishine 10n of eicosanoids, angiotensin II and monocyte-macrophages releasing reactive oxygen species (ROS).Angiotensin converting enzyme inhibitors and early corticosteroid usage are prime therapies.Tonsillectomy should be considered.Other components of a therapeutic cocktail could be; (a) lutron rrst-8ans-wh thromboxane antogonist, (b) leukotriene antagonist, (c) platelet activating factor antagonist, (d) an anti-oxidant and (e) an anti-fibrotic agent like pentoxyfylline.In the new millenium, there will be focus on anti-proliferative measures like platelets dependent growth factor aptamers.
For unusual cases with rapid progression, the use of FK-506 or mycophenolate mofetil can be considered.